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赵兴洪

时间: 2021-09-27 点击次数:次 作者:



姓名

赵兴洪

政治面貌

中共党员

导师类型

硕士导师

办公地点

6308

职称/职务

特聘副教授

电子邮箱

xinghong.zhao@sicau.edu.cn

研究方向

新型环肽类抗生素研发、合成生物学

学术、技术组织任职/头衔

现任Frontiers in   Microbiology (IF=5.640, Top)客座编辑(Guest Editor)和Frontiers in Chemistry (IF=5.221) Review   Editor、荷兰皇家微生物学学会会员(2018至今)。

教育背景及工作经历

2021/08 四川农业大学 特聘副教授

2019/09–2021/08 荷兰格罗宁根大学 微生物与生化药学 博士后

2017/08–2020/06 荷兰格罗宁根大学 微生物与生化药学 理学博士

2015/09–2020/06 四川农业大学 基础兽医学 农学博士

2013/09–2015/06 四川农业大学 兽医学 兽医硕士

2009/09–2013/06 四川农业大学 药物制剂 工学学士

教学课程

生物技术制药、仪器分析(药)、中药学、药学专业英语

人才培养情况

在荷兰留学期间指导毕业硕士研究生1名,现正指导硕士生2名和本科生10名。

科研项目

(近五年)

1、新型环肽类抗生素研发,四川农业大学引进人才科研启动项目202108-202607,在研,主持

2、高效防治奶牛乳房炎新型抗菌肽兰希素的创制及其作用机制研究,四川省国际科技创新合作项目202201-202312,在研,主持

主要论著、

代表性论文

[1] Xinghong,   Zhao, Zhibo Li, and Oscar P. Kuipers. "Mimicry of a Non-ribosomally   Produced Antimicrobial, Brevicidine, by Ribosomal Synthesis and   Post-translational Modification."   Cell Chemical Biology (2020).   (中科院分区升级版生物学一区,Top期刊,IF = 8.116

[2] Xinghong,   Zhao, Rubén Cebrián, Yuxin Fu, Rick Rink, Tjibbe Bosma, Gert N. Moll, and   Oscar P. Kuipers. "High-throughput screening for substrate   specificity-adapted mutants of the nisin dehydratase NisB." ACS Synthetic Biology (2020). (中科院分区升级版生化研究方法一区,Top期刊,IF = 5.110

[3] Xinghong,   Zhao, Zhongqiong Yin, Eefjan Breukink, Gert N. Moll, and Oscar P.   Kuipers. "An engineered double lipid II binding motifs-containing   lantibiotic displays potent and selective antimicrobial activity against Enterococcus   faecium." Antimicrobial Agents and   Chemotherapy (2020). (中科院分区升级版微生物学二区,Top期刊,IF = 5.191

[4] Xinghong,   Zhao, and Oscar P. Kuipers. "Nisin-and ripcin-derived hybrid   lanthipeptides display selective antimicrobial activity against   Staphylococcus aureus." ACS   Synthetic Biology (2021). (中科院分区升级版生化研究方法一区,Top期刊,IF = 5.110

[5] Xinghong,   Zhao, Yanli Xu,   Jakob H. Viel, and Oscar P. Kuipers. " Semisynthetic Macrocyclic   Lipo-lanthipeptides Display Antimicrobial Activity Against Bacterial   Pathogens." ACS Synthetic Biology (2021). (中科院分区升级版生化研究方法一区,Top期刊,IF = 5.110

[6] Xinghong,   Zhao, and Oscar P. Kuipers. "Synthesis of silver-nisin nanoparticles   with low cytotoxicity as antimicrobials against biofilm-forming   pathogens" Colloids and Surfaces   B: Biointerfaces (2021). (中科院分区升级版生物材料二区,Top期刊,IF = 5.268

[7] Xinghong,   Zhao, and Oscar P. Kuipers. "BrevicidineB, a new member of the   brevicidine family, displays an extended target specificity." Frontiers in Microbiology (2021). (中科院分区升级版生物学二区,Top期刊,IF = 5.640

[8] Xinghong,   Zhao, Xiaoqi Wang, Rhythm Shukla, Raj Kumar, Markus Weingarth, Eefjan   Breukink, and Oscar P Kuipers. " Brevibacillin 2V, a Novel Antimicrobial   Lipopeptide With an Exceptionally Low Hemolytic Activity." Frontiers in Microbiology (2021). (中科院分区升级版生物学二区,Top期刊,IF = 5.640

[9] Xinghong,   Zhao, Xiaoqi Wang, Rhythm Shukla, Raj Kumar, Markus Weingarth, Eefjan   Breukink, and Oscar P Kuipers. " Brevibacillin 2V exerts its bactericidal   activity via binding to Lipid II and permeabilizing cellular membranes."   Frontiers in Microbiology (2021). (中科院分区升级版生物学二区,Top期刊,IF = 5.640

[10] Xinghong, Zhao, Jiao Xu, Xu Song, Ruilin Jia, Zhongqiong Yin,   Anchun Cheng, Renyong Jia et al. "Antiviral effect of resveratrol in   ducklings infected with virulent duck enteritis virus." Antiviral research 130 (2016): 93-100. (JCR病毒学一区,IF = 4.271

[11] Xinghong, Zhao, Wenzhi Tong, Xu Song, Renyong Jia, Lixia Li,   Yuanfeng Zou, Changliang He et al. "Antiviral effect of resveratrol in   piglets infected with virulent Pseudorabies virus." Viruses 10, no. 9 (2018):   457. (JCR病毒学二区,IF = 3.811

[12] Xinghong, Zhao, Qiankun Cui, Qiuting Fu, Xu Song,   Renyong Jia, Yi Yang, Yuanfeng Zou et al. "Antiviral properties of   resveratrol against pseudorabies virus are associated with the inhibition of   IκB kinase activation." Scientific   reports 7, no. 1 (2017): 1-11.   (JCR综合一区,IF = 4.122


 

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