澳门新威尼斯线上下载

欧旭敏

时间: 2019-11-20 点击次数:次 作者:


姓名

欧旭敏

政治面貌

中共党员

导师类型

硕士研究生

办公地点

6207

职称/职务

讲师

电子邮箱

x.ou@sicau.edu.cn

研究方向

共用技术、人禽共患病毒性肝炎

学术、技术组织任职/头衔

四川省海外高层次留学人才、Frontiers   in Immunology杂志审稿人、教育部学位中心研究生论文评审专家

教育背景及工作经历

2019.07-至今:澳门新威尼斯线上下载预防兽医研究所,讲师

2017.09-2021.11:荷兰伊拉斯姆斯医学中心,医学博士

2012.09-2019.06:四川农业大学(直博),农学博士

2010.09-2012.06:黑龙江八一农垦大学,本科,农学学士

2008.10-2010.12:黑龙江大学,本科,工学学士

教学课程

生物信息

人才培养情况

担任硕士研究生导师,指导攻读科学硕士学位研究生5人,本科生2人。



科研项目

(近五年)


2020-012022-12干扰素α介导tRNA组改变在抗病毒基因翻译失常中的机理研究(10万)四川省科技厅,主持

2022-012024-12宿主tRNA调控鸭甲肝病毒在鸡胚细胞中翻译的分子机制(30万)国家自然科学基金,主持

主要论著、

代表性论文

1. Ou X, Cao J, Cheng A, Peppelenbosch MP, Pan Q.   Errors in translational decoding: tRNA wobbling or misincorporation? Plos Genetics 2019; 15(3): e1008017.

2. Ou X, Ma B, Zhang R, et al. A simplified qPCR   method revealing tRNAome remodeling upon infection by genotype 3 hepatitis E   virus. FEBS Lett 2020; 594(12): 2005-15.

3. Ou X, Peng W, Yang Z, et al. Evolutionarily   missing and conserved tRNA genes in human and avian. Infect Genet Evol 2020: 104460.

4. Zhang R, Noordam L, Ou X, et al. The biological   process of lysinetRNA charging is therapeutically targetable in   liver cancer. 2021; 41(1): 206-19.

5. Ou X, Yang Z, Zhu D, et al. Tracing genetic   signatures of bat-to-human coronaviruses and early transmission of North   American SARS-CoV-2. Transbound Emerg   Dis 2021.

6. Ou X, Wang M, Mao S, et al. Incompatible   Translation Drives a Convergent Evolution and Viral Attenuation During the   Development of Live Attenuated Vaccine. Frontiers   in Cellular and Infection Microbiology 2018; 8: 249-60.

7. Ou X, Mao S, Cao J, et al. Comparative analysis   of virus-host interactions caused by a virulent and an attenuated duck   hepatitis A virus genotype 1. PLOS ONE   2017; 12(6): e0178993.

8. Zhang R, Noordam L, Ou X, et al. The biological   process of lysine-tRNA charging is therapeutically targetable in liver   cancer. Liver Int 2020; 41(1): 206-19.

9. Mao S, Ou X, Wang M, et al. Duck hepatitis A   virus 1 has lymphoid tissue tropism altering the organic immune responses of   mature ducks. Transbound Emerg Dis   2020.

10. Miao Z, Zhang S, Ou X, et al. Estimating the   Global Prevalence, Disease Progression, and Clinical Outcome of Hepatitis   Delta Virus Infection. The Journal of   Infectious Diseases 2019; 221(10):   1677-87.

11. Cao J, Ou X, Zhu D, et al. The 2A2 protein of   Duck hepatitis A virus type 1 induces apoptosis in primary cell culture. Virus Genes 2016: 1-9.

12. Li Y, Qu C, Yu P, Ou X, Pan Q, Wang W. The   Interplay between Host Innate Immunity and Hepatitis E Virus. Viruses 2019; 11(6): 541-60.

13. Zhu D, Chen H, Ou X, et al. Comparison of   immunohistochemistry and Ziehl-Neelsen staining for detecting the   distribution of Mycobacterium avium subsp avium in naturally infected   domestic Pekin ducks (Anas platyrhynchos domestica). Veterinary medicine and science 2019.

14. Wen X, Guo J, Sun D, et al. Mutations in VP0 and   2C Proteins of Duck Hepatitis A Virus Type 3 Attenuate Viral Infection and   Virulence. Vaccines (Basel) 2019; 7(3).

15. Zhu D-K, Song X-H, Wang J-B, et al. Outbreak of   Avian Tuberculosis in Commercial Domestic Pekin Ducks (Anas platyrhynchos   domestica). Avian Diseases 2016; 60(3): 677-80.

16. Xie J, Zeng Q, Wang M, et al. Transcriptomic   Characterization of a Chicken Embryo Model Infected With Duck Hepatitis A   Virus Type 1. Frontiers in Immunology   2018; 9.

17. Mao S, Wang M, Ou X, et al. Virologic and   Immunologic Characteristics in Mature Ducks with Acute Duck Hepatitis A Virus   1 Infection. Frontiers in Immunology   2017; 8.

18. Mao S, Ou X, Zhu D, et al. Development and   evaluation of indirect ELISAs for the detection of IgG, IgM and IgA1 against   duck hepatitis A virus 1. J Virol   Methods 2016; 237: 79-85.

19.

获奖、新药、新品种等


指导挑战杯、创青春、互联网+等双创项目获省级奖项(近五年,注获奖时间)

创新实验、科研兴趣计划项目(近五年,注立项时间)

授权专利、编著教材

用于人类基因组成熟tRNA谱检测的接头,引物组和试剂盒:授权号:ZL 201811302188.X.

社会服务

水禽病原检测与流行病学调查。


 

上一篇:何冉

下一篇:毛赛